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Details on Person Rothfels, Karen, 2019-08-14

Class:IdInstanceEdit:9658450
_displayNameRothfels, Karen, 2019-08-14
_timestamp2019-08-14 14:29:49
author[Person:1226097] Rothfels, Karen
dateTime2019-08-14 14:29:42
(created)[CatalystActivity:9658443] protein serine/threonine phosphatase activity of S-GCC MRAS:GTP:SHOC2:PP1 [plasma membrane]
[EntityWithAccessionedSequence:9658444] SHOC2 [cytosol] [Homo sapiens]
[Reaction:9658445] MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs [Homo sapiens]
[GroupModifiedResidue:9658446] S-geranylgeranyl-L-cysteine (geranylgeranyl group) at 205
[Complex:9658447] S-GCC MRAS:GTP:SHOC2:PP1 [plasma membrane] [Homo sapiens]
[Complex:9658448] S-GCC MRAS:GTP [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9658449] S-GGC MRAS [plasma membrane] [Homo sapiens]
[StableIdentifier:9658451] R-HSA-9658449.1
[StableIdentifier:9658452] R-HSA-9658447.1
[StableIdentifier:9658453] R-HSA-9658445.2
List all 12 refering instances
(modified)[PathwayDiagram:5673003] Diagram of RAF/MAP kinase cascade, Signaling by high-kinase activity BRAF mutants, Signaling by moderate kinase activity BRAF mutants, Paradoxical activation of RAF signaling by kinase inactive BRAF, Signaling by BRAF and RAF1 fusions, RAS signaling downstream of NF1 loss-of-function variants, Signaling downstream of RAS mutants, Signaling by MAP2K mutants, Signaling by MAPK mutants, Signaling by RAF1 mutants, SHOC2 M1731 mutant abolishes MRAS complex function, Gain-of-function MRAS complexes activate RAF signaling, Signaling by RAS GAP mutants, Signaling by RAS GEF mutants, and Signaling by RAS GTPase mutants
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No pathways have been reviewed or authored by Rothfels, Karen, 2019-08-14 (9658450)
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