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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person OGG1 R46Q [nucleoplasm]

Class:IdEntityWithAccessionedSequence:9657113
_displayNameOGG1 R46Q [nucleoplasm]
_timestamp2019-08-15 13:50:51
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9657117] Orlic-Milacic, Marija, 2019-08-07
disease[Disease:1500689] cancer
[Disease:1655484] kidney cancer
[Disease:1655483] renal clear cell carcinoma
endCoordinate345
hasModifiedResidue[ReplacedResidue:9657109] L-arginine 46 replaced with L-glutamine
literatureReference[LiteratureReference:9657114] Alterations of the DNA repair gene OGG1 in human clear cell carcinomas of the kidney
[LiteratureReference:9657125] Effect of single mutations in the OGG1 gene found in human tumors on the substrate specificity of the Ogg1 protein
[LiteratureReference:9658493] The R46Q, R131Q and R154H polymorphs of human DNA glycosylase/beta-lyase hOgg1 severely distort the active site and DNA recognition site but do not cause unfolding
modified[InstanceEdit:9657126] Orlic-Milacic, Marija, 2019-08-07
[InstanceEdit:9658496] Orlic-Milacic, Marija, 2019-08-15
nameOGG1 R46Q
OGG1 Arg46Gln
referenceEntity[ReferenceGeneProduct:60888] UniProt:O15527 OGG1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9657121] R-HSA-9657113.1
startCoordinate1
(hasMember)[CandidateSet:9656300] OGG1 mutants (8oxoG hydrolysis) [nucleoplasm] [Homo sapiens]
[CandidateSet:9657137] OGG1 mutants (FapyG hydrolysis) [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by OGG1 R46Q [nucleoplasm] (9657113)
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