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Details on Person Cysmethynil [cytosol]

Class:Id	ChemicalDrug:9656757
_displayName	Cysmethynil [cytosol]
_timestamp	2019-08-02 16:42:45
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9656758] Rothfels, Karen, 2019-08-02
disease	[Disease:1500689] cancer
literatureReference	[LiteratureReference:9656501] Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer [LiteratureReference:9656508] Inhibition of isoprenylcysteine carboxylmethyltransferase augments BCR-ABL1 tyrosine kinase inhibition-induced apoptosis in chronic myeloid leukemia [LiteratureReference:9653386] Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth
name	Cysmethynil
referenceEntity	[ReferenceTherapeutic:9656545] Cysmethynil [PubChem Compound:6918831]
stableIdentifier	[StableIdentifier:9656759] R-ALL-9656757.1
(activeUnit)	[NegativeRegulation:9656786] Negative regulation by 'ICMT:Zn2+:Cysmethynil [endoplasmic reticulum membrane]'
(hasComponent)	[Complex:9656776] ICMT:Zn2+:Cysmethynil [endoplasmic reticulum membrane] [Homo sapiens]
(input)	[Reaction:9656775] Cysmethynil binds ICMT:Zn2+ [Homo sapiens]
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No pathways have been reviewed or authored by Cysmethynil [cytosol] (9656757)