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Details on Person Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)

Class:IdLiteratureReference:9656458
_displayNameDiscovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)
_timestamp2019-08-02 15:39:06
author[Person:9656459] Judd, Weston R
[Person:9656447] Slattum, Paul M
[Person:9656460] Hoang, Khanh C
[Person:9656448] Bhoite, Leena
[Person:9656456] Valppu, Liisa
[Person:9656449] Alberts, Glen
[Person:9656457] Brown, Brita
[Person:9656461] Roth, Bruce
[Person:9656450] Ostanin, Kirill
[Person:9656451] Huang, Liwen
[Person:9656452] Wettstein, Daniel
[Person:9656453] Richards, Burt
[Person:9656455] Willardsen, J Adam
created[InstanceEdit:9656454] Rothfels, Karen, 2019-08-02
journalJ. Med. Chem.
pages5031-47
pubMedIdentifier21661760
titleDiscovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT)
volume54
year2011
(literatureReference)[Reaction:9656775] Cysmethynil binds ICMT:Zn2+ [Homo sapiens]
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No pathways have been reviewed or authored by Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) (9656458)