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Details on Person activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane]

Class:IdComplex:9656185
_displayNameactivated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane]
_timestamp2019-10-28 19:20:25
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9656184] Rothfels, Karen, 2019-07-27
disease[Disease:9651116] Costello syndrome
[Disease:9651118] LEOPARD syndrome
[Disease:6802289] Noonan syndrome
[Disease:1500689] cancer
[Disease:6788675] hypertrophic cardiomyopathy
hasComponent
isChimericFALSE
modified[InstanceEdit:9665048] Rothfels, Karen, 2019-10-28
nameactivated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9656186] R-HSA-9656185.1
(diseaseEntity)[EntityFunctionalStatus:9656200] gain_of_function of activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane]
(input)[Reaction:9656209] Dissociation of RAS:RAF1 mutant complex [Homo sapiens]
(output)[Reaction:9656214] MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919647] Update Tracker - [Complex:9656185] activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] - v90:[updateContainedComponent]
[_UpdateTracker:9928680] Update Tracker - [Complex:9656185] activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] - v91:[updateContainedComponent]
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No pathways have been reviewed or authored by activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (9656185)
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