Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person p-S621-RAF1 P261T [cytosol]

Class:Id	EntityWithAccessionedSequence:9656115
_displayName	p-S621-RAF1 P261T [cytosol]
_timestamp	2019-07-27 15:19:02
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9656116] Rothfels, Karen, 2019-07-27
crossReference	[DatabaseIdentifier:9655967] COSMIC:COSV52576947
disease	[Disease:1614289] melanoma [Disease:6802289] Noonan syndrome
endCoordinate	648
hasModifiedResidue	[ModifiedResidue:109785] O-phospho-L-serine at 621 [ReplacedResidue:9655914] L-proline 261 replaced with L-threonine
literatureReference	[LiteratureReference:9655515] Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation [LiteratureReference:9655523] Spectrum of mutations in Noonan syndrome and their correlation with phenotypes
name	p-S621-RAF1 P261T RAF proto-oncogene serine/threonine-protein kinase Raf-1 C-RAF cRaf
referenceEntity	[ReferenceGeneProduct:58255] UniProt:P04049 RAF1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9656117] R-HSA-9656115.1
startCoordinate	1
(hasMember)	[CandidateSet:9656159] p-S621 RAF1 CR2 mutants [cytosol] [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by p-S621-RAF1 P261T [cytosol] (9656115)