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Details on Person Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

Class:IdLiteratureReference:9655727
_displayNameProteolytic properties of single-chain factor XII: a mechanism for triggering contact activation
_timestamp2019-07-26 00:59:40
author[Person:9653221] Ivanov, Ivan
[Person:9653253] Matafonov, Anton
[Person:158337] Sun, MF
[Person:9653246] Cheng, Qiufang
[Person:9653232] Dickeson, S Kent
[Person:9653236] Verhamme, Ingrid M
[Person:9653844] Emsley, Jonas
[Person:158160] Gailani, D
created[InstanceEdit:9655724] Shamovsky, Veronica, 2019-07-26
journalBlood
pages1527-1537
pubMedIdentifier28069606
titleProteolytic properties of single-chain factor XII: a mechanism for triggering contact activation
volume129
year2017
(literatureReference)[Reaction:9655840] FXIIa is cleaved to β-FXIIa [Homo sapiens]
[Reaction:9855735] factor XII:polyanionic activator -> factor XIIa + polyanionic activator (autocatalysis) [Homo sapiens]
[Reaction:9909048] prekallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor:factor XII (FXII catalyst) [Homo sapiens]
[Summation:9651462] The contact activation system (CAS) is a plasma protease cas...
[Summation:9655043] Factor XII (FXII, F12 or Hageman factor) is a serine proteas...
[Summation:9655747] The plasma protein factor XII (FXII, F12 or Hageman factor) ...
[Summation:9656381] Coagulation factor XII (FXII) is secreted as an inactive zym...
[Summation:9855753] The contact activation system (CAS) is a plasma serine prote...
[Summation:9857899] Autocatalytic cleavage of a single peptide bond after Arg372...
[Summation:9857963] The plasma kallikrein-kinin system (KKS) is a proteolytic ca...
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