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Details on Person Posttranslational Modifications of RAS Proteins

Class:IdLiteratureReference:9653444
_displayNamePosttranslational Modifications of RAS Proteins
_timestamp2019-07-11 15:04:23
author[Person:9653443] Ahearn, Ian
[Person:9653442] Zhou, Mo
[Person:2685392] Philips, Mark R
created[InstanceEdit:9653445] Rothfels, Karen, 2019-07-11
journalCold Spring Harb Perspect Med
pubMedIdentifier29311131
titlePosttranslational Modifications of RAS Proteins
volume8
year2018
(literatureReference)[Reaction:9647977] ICMT methylates S-Farn RAS proteins [Homo sapiens]
[Reaction:9647978] pro-RAS proteins are farnesylated [Homo sapiens]
[Reaction:9647982] S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated [Homo sapiens]
[Reaction:9647994] RAS proteins are depalmitoylated [Homo sapiens]
[Reaction:9647999] RCE1 cleaves S-Farn proRAS proteins [Homo sapiens]
[Pathway:9648002] RAS processing [Homo sapiens]
[Reaction:9653503] KRAS4B is phosphorylated on serine 181 [Homo sapiens]
[Reaction:9653585] S-Farn-Me KRAS4B binds calmodulin [Homo sapiens]
[BlackBoxEvent:9653592] pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane [Homo sapiens]
[Reaction:9653595] pS181-S-Farn-Me KRAS4B binds BCL2L1 [Homo sapiens]
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