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Details on Person PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis

Class:IdLiteratureReference:9653428
_displayNamePKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
_timestamp2019-07-11 15:04:08
author[Person:2685232] Bivona, Trever G
[Person:9653424] Quatela, Steven E
[Person:9653434] Bodemann, Brian O
[Person:2685083] Ahearn, Ian M
[Person:9653429] Soskis, Michael J
[Person:6788759] Mor, Adam
[Person:9653431] Miura, John
[Person:9653435] Wiener, Heidi H
[Person:9653427] Wright, Latasha
[Person:9653432] Saba, Shahryar G
[Person:9653433] Yim, Duke
[Person:9653430] Fein, Adam
[Person:2685253] Pérez De Castro, Ignacio
[Person:9653425] Li, Chi
[Person:140401] Thompson, CB
[Person:2685057] Cox, Adrienne D
[Person:2685392] Philips, Mark R
created[InstanceEdit:9653426] Rothfels, Karen, 2019-07-11
journalMol. Cell
pages481-93
pubMedIdentifier16483930
titlePKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
volume21
year2006
(literatureReference)[Complex:9653576] p-S181-S-Farn-Me KRAS4B:BCL2L1 [mitochondrial outer membrane] [Homo sapiens]
[Reaction:9653503] KRAS4B is phosphorylated on serine 181 [Homo sapiens]
[BlackBoxEvent:9653592] pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane [Homo sapiens]
[Reaction:9653595] pS181-S-Farn-Me KRAS4B binds BCL2L1 [Homo sapiens]
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