Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person p-T185,Y187 MAPK1 P58L [cytosol]

Class:Id	EntityWithAccessionedSequence:9652806
_displayName	p-T185,Y187 MAPK1 P58L [cytosol]
_timestamp	2019-07-03 19:47:16
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9652805] Rothfels, Karen, 2019-07-03
crossReference	[DatabaseIdentifier:9652704] COSMIC:COSV53185734
disease	[Disease:1248679] head and neck squamous cell carcinoma [Disease:1500699] lung cancer
endCoordinate	360
hasModifiedResidue	[ReplacedResidue:9652776] L-proline 58 replaced with L-leucine [ModifiedResidue:3006594] O-phospho-L-threonine at 185 [ModifiedResidue:109851] O4'-phospho-L-tyrosine at 187
literatureReference	[LiteratureReference:9652693] Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants [LiteratureReference:9606531] Mutational landscape of aggressive cutaneous squamous cell carcinoma [LiteratureReference:9646931] Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients
name	p-T185,Y187 MAPK1 P58L ERK2 Mitogen-activated protein kinase 1 (EC 2.7.1.-) (Extracellular signal- regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Mitogen-activated protein kinase 1 Extracellular signal-regulated kinase 2 Mitogen-activated protein kinase 2 MAP kinase 2 MAPK 2 p42-MAPK ERT1 ERK-2
referenceEntity	[ReferenceGeneProduct:59283] UniProt:P28482 MAPK1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9652807] R-HSA-9652806.1
startCoordinate	2
(hasMember)	[CandidateSet:9652813] constitutively active MAPK1 mutants [cytosol] [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by p-T185,Y187 MAPK1 P58L [cytosol] (9652806)