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Details on Person Orlic-Milacic, Marija, 2019-06-28

Class:IdInstanceEdit:9652372
_displayNameOrlic-Milacic, Marija, 2019-06-28
_timestamp2019-06-28 18:51:09
author[Person:1169272] Orlic-Milacic, Marija
dateTime2019-06-28 18:51:07
(authored)[Pathway:8853884] Transcriptional Regulation by VENTX [Homo sapiens]
[Reaction:8853890] VENTX binds the IL6 gene promoter [Homo sapiens]
[Reaction:8853898] VENTX binds the CSF1R (M-CSF-R) gene promoter [Homo sapiens]
[BlackBoxEvent:8853908] VENTX stimulates CSF1R (M-CSF-R) expression [Homo sapiens]
[BlackBoxEvent:8853911] VENTX stimulates TP53 gene expression [Homo sapiens]
[Reaction:8853915] VENTX binds the TP53 gene promoter [Homo sapiens]
[Reaction:8853920] VENTX binds the CDKN2A gene [Homo sapiens]
[BlackBoxEvent:8853921] VENTX stimulates p16-INK4A transcription [Homo sapiens]
[BlackBoxEvent:8853956] Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 and inhibited by VENTX:TCF4,LEF1 [Homo sapiens]
[Reaction:8853965] VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 [Homo sapiens]
(modified)[PathwayDiagram:1227987] Diagram of Signaling by ERBB2, Constitutive Signaling by Overexpressed ERBB2, Signaling by ERBB2 KD Mutants, Resistance of ERBB2 KD mutants to trastuzumab, Resistance of ERBB2 KD mutants to lapatinib, Resistance of ERBB2 KD mutants to neratinib, Resistance of ERBB2 KD mutants to osimertinib, Resistance of ERBB2 KD mutants to afatinib, Resistance of ERBB2 KD mutants to tesevatinib, Resistance of ERBB2 KD mutants to sapitinib, Resistance of ERBB2 KD mutants to AEE788, Signaling by ERBB2 ECD mutants, Signaling by ERBB2 TMD/JMD mutants, and Drug resistance in ERBB2 TMD/JMD mutants
[Reaction:1963582] Trans-autophosphorylation of ERBB2 heterodimers [Homo sapiens]
[Reaction:9652264] ERBB2 binds TKIs [Homo sapiens]
[Summation:9652268] ERBB2 signaling is inhibited by binding of ERBB2 to ERBB2-di...
[Reaction:9652277] ERBB2 binds trastuzumab [Homo sapiens]
(revised)[BlackBoxEvent:3790130] Regulation of IL6 transcription [Homo sapiens]
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2019-06-28 (9652372)