Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person MAP2K1 K57N [cytosol]

Class:IdEntityWithAccessionedSequence:9652050
_displayNameMAP2K1 K57N [cytosol]
_timestamp2019-06-27 20:11:00
compartment[Compartment:70101] cytosol
created[InstanceEdit:9652049] Rothfels, Karen, 2019-06-27
crossReference[DatabaseIdentifier:9651779] COSMIC:COSV61068581
[DatabaseIdentifier:9651821] COSMIC:COSV61070413
disease[Disease:9647528] biliary tract cancer
[Disease:4791250] colorectal cancer
[Disease:1500699] lung cancer
endCoordinate393
hasModifiedResidue[ReplacedResidue:9651872] L-lysine 57 replaced with L-asparagine
literatureReference[LiteratureReference:9651979] Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma
[LiteratureReference:9651955] Mutation analysis of BRAF, MEK1 and MEK2 in 15 ovarian cancer cell lines: implications for therapy
nameMAP2K1 K57N
MEK1
Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1)
Dual specificity mitogen-activated protein kinase kinase 1
MAP kinase kinase 1
MAPKK 1
ERK activator kinase 1
MAPK/ERK kinase 1
referenceEntity[ReferenceGeneProduct:59503] UniProt:Q02750 MAP2K1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9652051] R-HSA-9652050.1
startCoordinate2
(hasComponent)[Complex:9652113] MAP2K1 K57N dimer [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by MAP2K1 K57N [cytosol] (9652050)