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Details on Person Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
| Class:Id | LiteratureReference:9649423 |
| _displayName | Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways |
| _timestamp | 2019-06-14 10:16:05 |
| author | [Person:9649427] Mizuki, M [Person:9649428] Fenski, R [Person:9649415] Halfter, H [Person:9027154] Matsumura, I [Person:5318436] Schmidt, R [Person:9622472] Müller, C [Person:9649429] Grüning, W [Person:9649421] Kratz-Albers, K [Person:9649418] Serve, S [Person:9649419] Steur, C [Person:9649420] Büchner, T [Person:9649426] Kienast, J [Person:9027166] Kanakura, Y [Person:9649413] Berdel, W E [Person:9649416] Serve, H |
| created | [InstanceEdit:9649422] Varusai, Thawfeek, 2019-06-14 |
| journal | Blood |
| modified | [InstanceEdit:9649431] Varusai, Thawfeek, 2019-06-14 |
| pages | 3907-14 |
| pubMedIdentifier | 11090077 |
| title | Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways |
| volume | 96 |
| year | 2000 |
| (literatureReference) | [Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens] [Reaction:9695845] FLT3 mutant dimers:GRB2 bind SOS1 [Homo sapiens] [Reaction:9695853] FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS [Homo sapiens] [Reaction:9698005] FLT3 ITD mutants phosphorylate STAT5 [Homo sapiens] [Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens] [EntityWithAccessionedSequence:9696032] FLT3 R595_L601dup [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9696035] p-6Y-FLT3 R595_L601dup [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9696037] FLT3 Y599_G613dup [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9696039] p-6Y-FLT3 Y599_G613dup [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9696043] FLT3 Y591_V592insVDFREDREHH [plasma membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways (9649423)