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Details on Person Addition of GlcNAc to the glycan on the A arm

Class:Id	Reaction:964768
_displayName	Addition of GlcNAc to the glycan on the A arm
_doRelease	TRUE
_timestamp	2010-12-02 14:38:38
authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
catalystActivity	[CatalystActivity:964758] alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity of MGAT1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:964731] Jassal, B, 2010-09-17
edited	[InstanceEdit:964731] Jassal, B, 2010-09-17
input	[SimpleEntity:964740] (GlcNAc)2 (Man)5 (Asn)1 [Golgi lumen] [SimpleEntity:914003] UDP-GlcNAc [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:964745] Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene [LiteratureReference:964732] Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation
modified	[InstanceEdit:964770] Jassal, B, 2010-09-17 [InstanceEdit:964836] Jassal, B, 2010-09-17 [InstanceEdit:964839] Jassal, B, 2010-09-17 [InstanceEdit:1008193] Jassal, B, 2010-11-10 [InstanceEdit:1022125] Jassal, B, 2010-11-17 [InstanceEdit:1028800] Jassal, B, 2010-11-18 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of GlcNAc to the glycan on the A arm
output	[SimpleEntity:205687] UDP [Golgi lumen] [SimpleEntity:964837] (GlcNAc)3 (Man)5 (Asn)1 [Golgi lumen]
precedingEvent	[Reaction:964830] Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 [Homo sapiens] [Reaction:964825] Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 [Homo sapiens] [Reaction:964737] Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:1028799] Gagneux, P, 2010-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105288] R-HSA-964768.2
summation	[Summation:964766] This is the first committed step in the synthesis of complex...
(hasEvent)	[Pathway:964739] N-glycan trimming and elongation in the cis-Golgi [Homo sapiens]
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