Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person GSDMD(1-275) [cytosol]

Class:IdEntityWithAccessionedSequence:9647641
_displayNameGSDMD(1-275) [cytosol]
_timestamp2019-06-03 02:59:15
compartment[Compartment:70101] cytosol
created[InstanceEdit:9647682] Shamovsky, Veronica, 2019-06-03
endCoordinate275
nameGSDMD(1-275)
Gasdermin-D(1-275)
Gasdermin-D, N-terminal
GSDMD_HUMAN
referenceEntity[ReferenceGeneProduct:53562] UniProt:P57764 GSDMD [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9647695] R-HSA-9647641.1
startCoordinate1
(activeUnit)[PositiveRegulation:9710343] Positive regulation by 'GSDMD(1-275):cardiolipin [mitochondrial outer membrane]'
(hasComponent)[Complex:9647626] GSDMD(1-275):cardiolipin [plasma membrane] [Homo sapiens]
[Complex:9647676] GSDMD oligomer:PIPs [plasma membrane] [Homo sapiens]
[Complex:9647692] GSDMD (1-275):PIPs [plasma membrane] [Homo sapiens]
[Complex:9710347] GSDMD(1-275):cardiolipin [mitochondrial outer membrane] [Homo sapiens]
(input)[Reaction:9647631] GSDMD (1-275) binds PIPs [Homo sapiens]
[Reaction:9647643] GSDMD (1-275) binds bacterial cardiolipin [Homo sapiens]
[Reaction:9647645] GSDMD oligomerizes into arc-, slit-shaped structures [Homo sapiens]
[Reaction:9693324] Disulfiram covalently modifies Cys191 in GSDMD [Homo sapiens]
[Reaction:9710353] GSDMD (1-275) binds cardiolipin [Homo sapiens]
(output)[BlackBoxEvent:9647680] CASP1 cleaves GSDMD [Homo sapiens]
[BlackBoxEvent:9947997] CASP5 cleaves GSDMD [Homo sapiens]
[BlackBoxEvent:9948146] CASP4 cleaves GSDMD [Homo sapiens]
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No pathways have been reviewed or authored by GSDMD(1-275) [cytosol] (9647641)