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Details on Person p-6Y-ERBB2 V842E [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9647206
_displayName	p-6Y-ERBB2 V842E [plasma membrane]
_timestamp	2019-05-30 20:00:11
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9647197] Orlic-Milacic, Marija, 2019-05-30
crossReference	[DatabaseIdentifier:9646708] COSMIC:COSV54067165
disease	[Disease:1500689] cancer [Disease:1614289] melanoma
endCoordinate	1255
hasModifiedResidue	[ReplacedResidue:9646705] L-valine 842 replaced with L-glutamic acid [ModifiedResidue:1248700] O4'-phospho-L-tyrosine at 1023 [ModifiedResidue:1248685] O4'-phospho-L-tyrosine at 1139 [ModifiedResidue:1248708] O4'-phospho-L-tyrosine at 1196 [ModifiedResidue:1248692] O4'-phospho-L-tyrosine at 1221 [ModifiedResidue:1248701] O4'-phospho-L-tyrosine at 1222 [ModifiedResidue:1248689] O4'-phospho-L-tyrosine at 1248
literatureReference	[LiteratureReference:9646947] Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma
name	p-6Y-ERBB2 V842E p-6Y-HER2 V842E p-6Y-ERBB2 Val842Glu p-6Y-HER2 Val842Glu
referenceEntity	[ReferenceGeneProduct:54422] UniProt:P04626 ERBB2 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9647221] R-HSA-9647206.1
startCoordinate	23
(hasCandidate)	[CandidateSet:9647244] p-6Y-ERBB2 KD mutants [plasma membrane] [Homo sapiens] [CandidateSet:9654674] p-6Y-ERBB2 V842I,(p-6Y-ERBB2 V842E) [plasma membrane] [Homo sapiens] [CandidateSet:9664610] p-6Y-ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane] [Homo sapiens] [CandidateSet:9664999] p-6Y-ERBB2 KD mutants (EGFR,RAS) [plasma membrane] [Homo sapiens] [CandidateSet:9665035] p-6Y-ERBB2 KD mutants (EGFR,PLCG1) [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by p-6Y-ERBB2 V842E [plasma membrane] (9647206)