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Details on Person An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer

Class:IdLiteratureReference:9647026
_displayNameAn Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer
_timestamp2019-05-29 18:43:15
author[Person:9646949] Hanker, Ariella B
[Person:9647006] Brewer, Monica Red
[Person:9646939] Sheehan, Jonathan H
[Person:9646959] Koch, James P
[Person:9646937] Sliwoski, Gregory R
[Person:9646996] Nagy, Rebecca
[Person:9647012] Lanman, Richard
[Person:6801837] Berger, Michael F
[Person:9646802] Hyman, David M
[Person:6790436] Solit, David B
[Person:5662780] He, Jie
[Person:1181052] Miller, V
[Person:5672167] Cutler, Richard E
[Person:9646431] Lalani, Alshad S
[Person:9646972] Cross, Darren
[Person:5683787] Lovly, Christine M
[Person:9647020] Meiler, Jens
[Person:2399806] Arteaga, Carlos L
created[InstanceEdit:9647017] Orlic-Milacic, Marija, 2019-05-29
journalCancer Discov
pages575-585
pubMedIdentifier28274957
titleAn Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer
volume7
year2017
(literatureReference)[EntityWithAccessionedSequence:9646823] ERBB2 T798I [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9646825] ERBB2 T798M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9646827] ERBB2 L869R [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9647202] p-6Y-ERBB2 T798I [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9647213] p-6Y-ERBB2 L869R [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9647218] p-6Y-ERBB2 T798M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9654615] p-Y-ERBB2 T798M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9654618] p-Y-ERBB2 T798I [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9654730] p-Y-ERBB2 L869R [plasma membrane] [Homo sapiens]
[Pathway:1227990] Signaling by ERBB2 in Cancer [Homo sapiens]
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No pathways have been reviewed or authored by An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer (9647026)