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Details on Person Tesevatinib [cytosol]
| Class:Id | ChemicalDrug:9646810 |
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| _displayName | Tesevatinib [cytosol] |
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| _timestamp | 2021-03-15 10:08:10 |
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| compartment | [Compartment:70101] cytosol |
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| created | [InstanceEdit:9646809] Orlic-Milacic, Marija, 2019-05-29 |
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| crossReference | [DatabaseIdentifier:9717745] ChEBI:167674 |
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| disease | [Disease:1500689] cancer |
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| modified | [InstanceEdit:9717734] Stephan, Ralf, 2021-03-15 |
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| name | Tesevatinib
EXEL-7647
XL-647
KD-019
XL647 |
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| referenceEntity | [ReferenceTherapeutic:9646808] tesevatinib [Guide to Pharmacology:7944] |
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| stableIdentifier | [StableIdentifier:9646811] R-ALL-9646810.2 |
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| (activeUnit) | [NegativeRegulation:9649937] Negative regulation by 'Tesevatinib:ERBB2 KD mutant heterodimers [plasma membrane]' |
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| (hasComponent) | [Complex:9649890] Tesevatinib:ERBB2 KD mutant heterodimers [plasma membrane] [Homo sapiens]
[Complex:9665134] ERBB2 KD mutants:tesevatinib [plasma membrane] [Homo sapiens] |
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| (hasMember) | [DefinedSet:9652360] lapatinib, neratinib, afatinib, AZ5104, tesevatinib, canertinib, sapitinib, CP-724714, AEE78 [cytosol]
[CandidateSet:9654997] neratinib,osimertinib,tesevatinib,(afatinib,sapitinib) [cytosol]
[DefinedSet:9655207] AZ5104,afatinib,tesevatinib [cytosol] [Homo sapiens]
[DefinedSet:9655239] lapatinib,tesevatinib [cytosol]
[DefinedSet:9665127] TKIs (ERBB2) [cytosol] |
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| (input) | [FailedReaction:9665315] ERBB2 T733I does not bind tesevatinib [Homo sapiens] |
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No pathways have been reviewed or authored by Tesevatinib [cytosol] (9646810)
