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Details on Person Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

Class:IdLiteratureReference:9646758
_displayNameIntra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
_timestamp2019-05-28 17:43:39
author[Person:9646753] Ng, Charlotte K Y
[Person:5638104] Martelotto, Luciano G
[Person:9646754] Gauthier, Arnaud
[Person:9646750] Wen, Huei-Chi
[Person:9646741] Piscuoglio, Salvatore
[Person:9646746] Lim, Raymond S
[Person:9646748] Cowell, Catherine F
[Person:9646757] Wilkerson, Paul M
[Person:9646756] Wai, Patty
[Person:9646742] Rodrigues, Daniel N
[Person:9646752] Arnould, Laurent
[Person:2023713] Geyer, FC
[Person:9646747] Bromberg, Silvio E
[Person:9646744] Lacroix-Triki, Magali
[Person:2023277] Penault-Llorca, F
[Person:9646751] Giard, Sylvia
[Person:1226111] Sastre-Garau, X
[Person:2011670] Natrajan, R
[Person:9646755] Norton, Larry
[Person:9646745] Cottu, Paul H
[Person:9646749] Weigelt, Britta
[Person:2011774] Vincent-Salomon, A
[Person:2011697] Reis-Filho, JS
created[InstanceEdit:9646743] Orlic-Milacic, Marija, 2019-05-28
journalGenome Biol.
pages107
pubMedIdentifier25994018
titleIntra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
volume16
year2015
(literatureReference)[EntityWithAccessionedSequence:9646737] ERBB2 I767M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9647211] p-6Y-ERBB2 I767M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9654303] p-Y-ERBB2 I767M [plasma membrane] [Homo sapiens]
[Summation:9664919] Many EGFR-binding ERBB2 KD mutants were shown to activate PI...
[Summation:9664930] For the following EGFR-binding ERBB2 KD mutants that activat...
[Summation:9664945] For the following EGFR-binding ERBB2 KD mutants that were sh...
[Pathway:9664565] Signaling by ERBB2 KD Mutants [Homo sapiens]
[Reaction:9664588] ERBB2 KD mutants trans-autophosphorylate [Homo sapiens]
[Reaction:9664646] Phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 bind PI3K [Homo sapiens]
[Reaction:9664664] PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 [Homo sapiens]
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No pathways have been reviewed or authored by Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification (9646758)