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Details on Person Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
| Class:Id | LiteratureReference:9646758 |
| _displayName | Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification |
| _timestamp | 2019-05-28 17:43:39 |
| author | [Person:9646753] Ng, Charlotte K Y [Person:5638104] Martelotto, Luciano G [Person:9646754] Gauthier, Arnaud [Person:9646750] Wen, Huei-Chi [Person:9646741] Piscuoglio, Salvatore [Person:9646746] Lim, Raymond S [Person:9646748] Cowell, Catherine F [Person:9646757] Wilkerson, Paul M [Person:9646756] Wai, Patty [Person:9646742] Rodrigues, Daniel N [Person:9646752] Arnould, Laurent [Person:2023713] Geyer, FC [Person:9646747] Bromberg, Silvio E [Person:9646744] Lacroix-Triki, Magali [Person:2023277] Penault-Llorca, F [Person:9646751] Giard, Sylvia [Person:1226111] Sastre-Garau, X [Person:2011670] Natrajan, R [Person:9646755] Norton, Larry [Person:9646745] Cottu, Paul H [Person:9646749] Weigelt, Britta [Person:2011774] Vincent-Salomon, A [Person:2011697] Reis-Filho, JS |
| created | [InstanceEdit:9646743] Orlic-Milacic, Marija, 2019-05-28 |
| journal | Genome Biol. |
| pages | 107 |
| pubMedIdentifier | 25994018 |
| title | Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification |
| volume | 16 |
| year | 2015 |
| (literatureReference) | [EntityWithAccessionedSequence:9646737] ERBB2 I767M [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9647211] p-6Y-ERBB2 I767M [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9654303] p-Y-ERBB2 I767M [plasma membrane] [Homo sapiens] [Summation:9664919] Many EGFR-binding ERBB2 KD mutants were shown to activate PI... [Summation:9664930] For the following EGFR-binding ERBB2 KD mutants that activat... [Summation:9664945] For the following EGFR-binding ERBB2 KD mutants that were sh... [Pathway:9664565] Signaling by ERBB2 KD Mutants [Homo sapiens] [Reaction:9664588] ERBB2 KD mutants trans-autophosphorylate [Homo sapiens] [Reaction:9664646] Phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 bind PI3K [Homo sapiens] [Reaction:9664664] PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 [Homo sapiens] |
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No pathways have been reviewed or authored by Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification (9646758)