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Query author contributions in Reactome

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Details on Person ERBB2 V842I [plasma membrane]

Class:IdEntityWithAccessionedSequence:9646703
_displayNameERBB2 V842I [plasma membrane]
_timestamp2019-05-28 16:36:44
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9646702] Orlic-Milacic, Marija, 2019-05-28
crossReference[DatabaseIdentifier:9646706] COSMIC:COSV54062791
[DatabaseIdentifier:9646709] COSMIC:COSM1666633
disease[Disease:1500689] cancer
[Disease:9630851] gallbladder adenocarcinoma
[Disease:2327989] bile duct carcinoma
[Disease:1500576] breast cancer
[Disease:2317358] endometrial cancer
[Disease:9631134] cervical squamous cell carcinoma
[Disease:1248674] large intestine cancer
[Disease:9632339] esophagus adenocarcinoma
[Disease:1500575] ovarian cancer
[Disease:2328198] pancreatic cancer
[Disease:1655494] prostate adenocarcinoma
[Disease:3310977] small intestine carcinoma
[Disease:1500687] stomach cancer
[Disease:2327997] pharynx cancer
[Disease:1493885] bladder carcinoma
[Disease:1655480] salivary gland cancer
[Disease:2317371] ovarian endometrioid neoplasm
endCoordinate1255
hasModifiedResidue[ReplacedResidue:9646701] L-valine 842 replaced with L-isoleucine
literatureReference[LiteratureReference:9646435] Activating HER2 mutations in HER2 gene amplification negative breast cancer
modified[InstanceEdit:9646712] Orlic-Milacic, Marija, 2019-05-28
[InstanceEdit:9646713] Orlic-Milacic, Marija, 2019-05-28
[InstanceEdit:9646718] Orlic-Milacic, Marija, 2019-05-28
nameERBB2 V842I
HER2 V842I
ERBB2 Val842Ile
HER2 Val842Ile
referenceEntity[ReferenceGeneProduct:54422] UniProt:P04626 ERBB2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9646704] R-HSA-9646703.1
startCoordinate23
(hasCandidate)[CandidateSet:9649470] ERBB2 KD mutants (sapitinib) [plasma membrane] [Homo sapiens]
(hasComponent)[Complex:9655250] ERBB2 V842I:ERBB4cyt1 heterodimers [plasma membrane] [Homo sapiens]
[Complex:9655252] ERBB2 V842I:ERBB4cyt2 heterodimer [plasma membrane] [Homo sapiens]
[Complex:9655254] EGF:EGFR:ERBB2 V842I [plasma membrane] [Homo sapiens]
[Complex:9655255] NRG1/2:ERBB3:ERBB2 V842I [plasma membrane] [Homo sapiens]
(hasMember)[CandidateSet:9646481] ERBB2 KD mutants [plasma membrane] [Homo sapiens]
[CandidateSet:9649436] ERBB2 KD mutants (neratinib) [plasma membrane] [Homo sapiens]
[CandidateSet:9649456] ERBB2 KD mutants (osimertinib) [plasma membrane] [Homo sapiens]
[CandidateSet:9649458] ERBB2 KD mutants (afatinib) [plasma membrane] [Homo sapiens]
[CandidateSet:9652385] ERBB2 V842I,(ERBB2 V842E) [plasma membrane] [Homo sapiens]
[CandidateSet:9664578] ERBB2 KD mutants (EGFR,ERBB3) [plasma membrane] [Homo sapiens]
[CandidateSet:9665226] ERBB2 KD mutants (trastuzumab resistant) [plasma membrane] [Homo sapiens]
[CandidateSet:9665282] ERBB2 KD mutants (lapatinib resistant) [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by ERBB2 V842I [plasma membrane] (9646703)