Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Aggresome dissociates from dynein and microtubule

Class:Id	Reaction:9646685
_displayName	Aggresome dissociates from dynein and microtubule
_doRelease	TRUE
_timestamp	2020-04-07 10:32:55
authored	[InstanceEdit:9646422] Varusai, Thawfeek, 2019-05-23
compartment	[Compartment:18667] microtubule organizing center
created	[InstanceEdit:9646683] Varusai, Thawfeek, 2019-05-28
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
input	[Complex:9646684] Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9646403] Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
modified	[InstanceEdit:9646695] Varusai, Thawfeek, 2019-05-28 [InstanceEdit:9655715] Varusai, Thawfeek, 2019-07-25 [InstanceEdit:9658415] D'Eustachio, Peter, 2019-08-13 [InstanceEdit:9663819] Varusai, Thawfeek, 2019-10-13 [InstanceEdit:9667360] Varusai, Thawfeek, 2019-11-12 [InstanceEdit:9667481] D'Eustachio, Peter, 2019-11-12 [InstanceEdit:9682019] Varusai, Thawfeek, 2020-04-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Aggresome dissociates from dynein and microtubule
output	[Complex:190599] Microtubule [cytosol] [Homo sapiens] [Complex:2029145] Dynein complex [cytosol] [Homo sapiens] [Complex:9646686] Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9646679] PolyUb-Misfolded proteins bind vimentin to form aggresome [Homo sapiens] [Reaction:9646383] Dynein motors transport misfolded proteins [Homo sapiens]
releaseDate	2019-12-10
reviewed	[InstanceEdit:9682018] Metzakopian, Emmanouil, 2019-05-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9646692] R-HSA-9646685.3
summation	[Summation:9646682] Misfolded proteins are transformed into aggresomes at the mi...
(hasEvent)	[Pathway:9646399] Aggrephagy [Homo sapiens]
(precedingEvent)	[Reaction:9615721] HSPA8 binds substrate [Homo sapiens] [Reaction:9646348] PolyUb-Misfolded Proteins:HDAC6 bind dynein motor [Homo sapiens] [Reaction:9646390] Misfolded proteins:HDAC6:Dynein motor binds microtubule [Homo sapiens] [Reaction:9685019] NBR1 and SQSTM1 bind ubiquitinated proteins in aggresome
[Change default viewing format]

No pathways have been reviewed or authored by Aggresome dissociates from dynein and microtubule (9646685)