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Details on Person p14ARF mutant does not translocate to the nucleus
| Class:Id | FailedReaction:9646295 |
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| _displayName | p14ARF mutant does not translocate to the nucleus |
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| _doRelease | TRUE |
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| _timestamp | 2019-08-14 14:47:27 |
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| authored | [InstanceEdit:9654178] Orlic-Milacic, Marija, 2019-06-28 |
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| compartment | [Compartment:70101] cytosol |
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| created | [InstanceEdit:9646297] Orlic-Milacic, Marija, 2019-05-22 |
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| disease | [Disease:1500689] cancer |
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| edited | [InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9658465] Orlic-Milacic, Marija, 2019-08-14 |
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| entityFunctionalStatus | [EntityFunctionalStatus:9646296] loss_of_function of p14ARF R21RfsTER47 [cytosol] |
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| input | [EntityWithAccessionedSequence:9646285] p14ARF V22Pfs*46 [cytosol] [Homo sapiens] |
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| isChimeric | FALSE |
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| literatureReference | [LiteratureReference:9646288] A melanoma-associated germline mutation in exon 1beta inactivates p14ARF |
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| modified | [InstanceEdit:9646302] Orlic-Milacic, Marija, 2019-05-22
[InstanceEdit:9646320] Orlic-Milacic, Marija, 2019-05-22
[InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9654179] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9654181] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9658472] Orlic-Milacic, Marija, 2019-08-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 |
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| name | p14ARF mutant does not translocate to the nucleus |
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| normalReaction |
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| releaseDate | 2019-09-10 |
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| reviewed | [InstanceEdit:9654174] Rizos, Helen, 2019-07-08
[InstanceEdit:9658468] Bennett, Dorothy C, 2019-08-12 |
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| reviewStatus | [ReviewStatus:9821382] five stars |
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| species | [Species:48887] Homo sapiens |
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| stableIdentifier | [StableIdentifier:9646298] R-HSA-9646295.2 |
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| summation | [Summation:9646301] A germline mutation affecting exon 1beta of the CDKN2A locus... |
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| (hasEvent) | [Pathway:9646303] Evasion of Oncogene Induced Senescence Due to p14ARF Defects [Homo sapiens]
[Pathway:9646304] Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects [Homo sapiens] |
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| (updatedInstance) | [_UpdateTracker:9835747] Update Tracker - [FailedReaction:9646295] p14ARF mutant does not translocate to the nucleus - v85:[modifyText] |
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No pathways have been reviewed or authored by p14ARF mutant does not translocate to the nucleus (9646295)
