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Details on Person p14ARF mutants do not bind C1QBP
| Class:Id | FailedReaction:9645766 |
| _displayName | p14ARF mutants do not bind C1QBP |
| _doRelease | TRUE |
| _timestamp | 2019-08-16 13:27:39 |
| authored | [InstanceEdit:9654178] Orlic-Milacic, Marija, 2019-06-28 |
| compartment | [Compartment:70101] cytosol |
| created | [InstanceEdit:9645768] Orlic-Milacic, Marija, 2019-05-17 |
| disease | [Disease:1500689] cancer |
| edited | [InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16 |
| entityFunctionalStatus | [EntityFunctionalStatus:9645767] loss_of_function of p14ARF LOF mutants (C1QBP) [cytosol] |
| input | [DefinedSet:9645736] p14ARF LOF mutants (C1QBP) [cytosol] [Homo sapiens] [Complex:9645765] C1QBP homotrimer [cytosol] [Homo sapiens] |
| isChimeric | FALSE |
| literatureReference | [LiteratureReference:9634089] Mitochondrial p32 is a critical mediator of ARF-induced apoptosis |
| modified | [InstanceEdit:9645781] Orlic-Milacic, Marija, 2019-05-17 [InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16 [InstanceEdit:9654179] Orlic-Milacic, Marija, 2019-07-16 [InstanceEdit:9654181] Orlic-Milacic, Marija, 2019-07-16 [InstanceEdit:9658540] Orlic-Milacic, Marija, 2019-08-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 |
| name | p14ARF mutants do not bind C1QBP |
| normalReaction |
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| releaseDate | 2019-09-10 |
| reviewed | [InstanceEdit:9654174] Rizos, Helen, 2019-07-08 [InstanceEdit:9658468] Bennett, Dorothy C, 2019-08-12 |
| reviewStatus | [ReviewStatus:9821382] five stars |
| species | [Species:48887] Homo sapiens |
| stableIdentifier | [StableIdentifier:9645770] R-HSA-9645766.2 |
| summation | [Summation:9645780] Several cancer-derived missense mutations in the CDKN2A gene... |
| (hasEvent) | [Pathway:9645722] Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function [Homo sapiens] |
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No pathways have been reviewed or authored by p14ARF mutants do not bind C1QBP (9645766)