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Details on Person p14ARF mutants do not bind C1QBP

Class:IdFailedReaction:9645766
_displayNamep14ARF mutants do not bind C1QBP
_doReleaseTRUE
_timestamp2019-08-16 13:27:39
authored[InstanceEdit:9654178] Orlic-Milacic, Marija, 2019-06-28
compartment[Compartment:70101] cytosol
created[InstanceEdit:9645768] Orlic-Milacic, Marija, 2019-05-17
disease[Disease:1500689] cancer
edited[InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16
entityFunctionalStatus[EntityFunctionalStatus:9645767] loss_of_function of p14ARF LOF mutants (C1QBP) [cytosol]
input[DefinedSet:9645736] p14ARF LOF mutants (C1QBP) [cytosol] [Homo sapiens]
[Complex:9645765] C1QBP homotrimer [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9634089] Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
modified[InstanceEdit:9645781] Orlic-Milacic, Marija, 2019-05-17
[InstanceEdit:9654176] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9654179] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9654181] Orlic-Milacic, Marija, 2019-07-16
[InstanceEdit:9658540] Orlic-Milacic, Marija, 2019-08-16
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namep14ARF mutants do not bind C1QBP
normalReaction
releaseDate2019-09-10
reviewed[InstanceEdit:9654174] Rizos, Helen, 2019-07-08
[InstanceEdit:9658468] Bennett, Dorothy C, 2019-08-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9645770] R-HSA-9645766.2
summation[Summation:9645780] Several cancer-derived missense mutations in the CDKN2A gene...
(hasEvent)[Pathway:9645722] Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function [Homo sapiens]
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No pathways have been reviewed or authored by p14ARF mutants do not bind C1QBP (9645766)