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Details on Person RRAGC,D exchanges GDP for GTP

Class:Id	Reaction:9645595
_displayName	RRAGC,D exchanges GDP for GTP
_timestamp	2019-06-02 10:24:18
authored	[InstanceEdit:9645589] May, Bruce, 2019-05-06
catalystActivity	[CatalystActivity:9647610] guanyl-nucleotide exchange factor activity of v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane]
compartment	[Compartment:17938] lysosomal membrane
created	[InstanceEdit:9645591] May, Bruce, 2019-05-13
edited	[InstanceEdit:9645589] May, Bruce, 2019-05-06
input	[SimpleEntity:29438] GTP [cytosol] [Complex:9646465] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9646247] Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability [LiteratureReference:9640284] Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms
modified	[InstanceEdit:9645601] May, Bruce, 2019-05-13 [InstanceEdit:9646273] May, Bruce, 2019-05-20 [InstanceEdit:9646478] May, Bruce, 2019-05-24 [InstanceEdit:9647611] May, Bruce, 2019-06-02
name	RRAGC,D exchanges GDP for GTP
output	[SimpleEntity:29420] GDP [cytosol] [Complex:9646462] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP:mTORC1:RHEB:GTP [lysosomal membrane] [Homo sapiens]
precedingEvent	[Reaction:9640195] RRAGA,B hydrolyzes GTP [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9645600] R-HSA-9645595.1
summation	[Summation:9646270] The Ragulator complex acts as a guanyl nucleotide exchange f...
(precedingEvent)	[Reaction:9646463] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP:mTORC1:RHEB:GTP binds TSC [Homo sapiens]
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No pathways have been reviewed or authored by RRAGC,D exchanges GDP for GTP (9645595)