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Details on Person Activators bind STAT5

Class:Id	Reaction:9645126
_displayName	Activators bind STAT5
_doRelease	TRUE
_timestamp	2019-09-11 08:18:25
authored	[InstanceEdit:9638040] Varusai, Thawfeek, 2019-02-23
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9645140] Varusai, Thawfeek, 2019-05-04
inferredFrom	[Reaction:9645128] Activators bind Stat5 [Mus musculus]
input	[DefinedSet:9645129] Activators of STAT5 [cytosol] [Homo sapiens] [CandidateSet:1295523] STAT5 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9604970] The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo
modified	[InstanceEdit:9645156] Varusai, Thawfeek, 2019-05-04 [InstanceEdit:9660646] Varusai, Thawfeek, 2019-09-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activators bind STAT5
output	[Complex:9645118] Activators of STAT5:STAT5 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9606784] Active FLT3:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens] [BlackBoxEvent:9606622] GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated [Homo sapiens] [Reaction:9604969] Active FLT3 binds PTPN11 [Homo sapiens] [BlackBoxEvent:9604767] FLT3LG dimer:FLT3 dimer autophosphorylates [Homo sapiens]
releaseDate	2019-06-12
reviewed	[InstanceEdit:9645124] Traer, Elie, 2019-05-03 [InstanceEdit:9646275] Joshi, Sunil, 2019-05-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9645142] R-HSA-9645126.3
summation	[Summation:9645120] Signal transducer and activator of transcription (STAT5A/STA...
(hasEvent)	[Pathway:9645135] STAT5 Activation [Homo sapiens]
(normalReaction)	[Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens]
(precedingEvent)	[Reaction:9645137] Activator phosphorylates STAT5 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776906] Update Tracker - [Reaction:9645126] Activators bind STAT5 - v74:[modifyText]
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No pathways have been reviewed or authored by Activators bind STAT5 (9645126)