Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:H2KZK4-1 F36D4.5
| Class:Id | ReferenceIsoform:9645047 |
|---|---|
| _chainChangeLog | chain:1-334 for 9645047 added on Thu May 2 2019 |
| _displayName | UniProt:H2KZK4-1 F36D4.5 |
| _timestamp | 2023-11-03 18:23:28 |
| chain | chain:1-334 |
| checksum | 897567EAF1B57958 |
| comment | FUNCTION Protease which deconjugates SUMO from some substrate proteins. Has isopeptidase but not SUMO-processing activity (By similarity). Collaborates with ubql-1 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234).SUBCELLULAR LOCATION Expressed in the pharynx, hypodermis, intestine, head neuron and tail neuron.DISRUPTION PHENOTYPE Worms lacking both POST and ubql-1 have a shorter lifespan and display an accumulation of ubiquitinated proteins in the nucleus.SIMILARITY Belongs to the DeSI family. |
| created | [InstanceEdit:9645038] Weiser, JD |
| description | recommendedName: Desumoylating isopeptidase 1 homolog shortName: DeSI-1 ecNumber: 3.4.-.- alternativeName: fullName evidence="6"Polyubiquitinated substrate transporter shortName evidence="6"POST |
| geneName | F36D4.5 |
| identifier | H2KZK4 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cytoplasm Hydrolase Nucleus Protease Reference proteome |
| modified | [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9750299] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | F36D4.5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | DESI1_CAEEL Q8MNS8 |
| sequenceLength | 334 |
| species | [Species:68320] Caenorhabditis elegans |
| variantIdentifier | H2KZK4-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:H2KZK4-1 F36D4.5 (9645047)
