Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:P61758-2 VBP1
| Class:Id | ReferenceIsoform:9645041 |
|---|---|
| _chainChangeLog | initiator methionine:1 for 9645041 added on Thu May 2 2019;chain:2-197 for 9645041 added on Thu May 2 2019;initiator methionine:1 for 9645041 removed on Fri Nov 03 2023;initiator methionine: for 9645041 added on Fri Nov 03 2023;initiator methionine: for 9645041 removed on Fri Aug 15 2025;initiator methionine:1 for 9645041 added on Fri Aug 15 2025 |
| _displayName | UniProt:P61758-2 VBP1 |
| _timestamp | 2025-08-15 21:55:27 |
| chain | initiator methionine:1 chain:2-197 |
| checksum | 973BA048048D948E |
| comment | FUNCTION Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.SUBUNIT Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Binds to the C-terminal part of VHL.INTERACTION In complex with VHL can translocate to the nucleus.ALTERNATIVE PRODUCTS Ubiquitous.SIMILARITY Belongs to the prefoldin subunit alpha family.SEQUENCE CAUTION Extended N-terminus. |
| created | [InstanceEdit:9645038] Weiser, JD |
| description | recommendedName: Prefoldin subunit 3 alternativeName: HIBBJ46 alternativeName: von Hippel-Lindau-binding protein 1 shortName: VBP-1 shortName: VHL-binding protein 1 |
| geneName | VBP1 PFDN3 |
| identifier | P61758 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Chaperone Cytoplasm Nucleus Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | VBP1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8989134] ENSEMBL:ENSG00000155959 VBP1 [Homo sapiens] |
| secondaryIdentifier | PFD3_HUMAN B2R8L5 B4DWR3 F5H2A7 O55228 Q15765 Q5JT81 Q86X96 |
| sequenceLength | 197 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | P61758-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P61758-2 VBP1 (9645041)
