Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein

Class:IdCatalystActivityReference:9643786
_displayNameprotein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein
_timestamp2019-04-04 17:05:19
catalystActivity[CatalystActivity:9029156] protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane]
created[InstanceEdit:9643047] Wu, G, 2019-04-04
literatureReference[LiteratureReference:9029077] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein
[LiteratureReference:9029071] RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development
(catalystActivityReference)[Reaction:9029155] JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 [Homo sapiens]
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No pathways have been reviewed or authored by protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein (9643786)