Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person ubiquitin protein ligase activity of PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor

Class:IdCatalystActivityReference:9643722
_displayNameubiquitin protein ligase activity of PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor
_timestamp2019-04-04 17:05:19
catalystActivity[CatalystActivity:9034385] ubiquitin protein ligase activity of PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane]
created[InstanceEdit:9643047] Wu, G, 2019-04-04
literatureReference[LiteratureReference:8953922] Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor
[LiteratureReference:8953919] Properties of the ubiquitin-pex5p thiol ester conjugate
[LiteratureReference:8953918] Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling
[LiteratureReference:8963760] PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation
[LiteratureReference:9033633] Distinct modes of ubiquitination of peroxisome-targeting signal type 1 (PTS1) receptor Pex5p regulate PTS1 protein import
(catalystActivityReference)[Reaction:9033485] PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 [Homo sapiens]
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No pathways have been reviewed or authored by ubiquitin protein ligase activity of PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor (9643722)
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