Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person ubiquitin protein ligase activity of US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

Class:IdCatalystActivityReference:9643689
_displayNameubiquitin protein ligase activity of US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
_timestamp2019-04-04 17:05:19
catalystActivity[CatalystActivity:8943123] ubiquitin protein ligase activity of US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane]
created[InstanceEdit:9643047] Wu, G, 2019-04-04
literatureReference[LiteratureReference:8943130] A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
[LiteratureReference:8943094] TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I
(catalystActivityReference)[BlackBoxEvent:8943080] TMEM129 polyubiquitinates HLA (MHC class I heavy chain) bound to cytomegalovirus US11 [Homo sapiens]
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