Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person histone methyltransferase activity (H3-K4 specific) of H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] Histone arginine methylation keeps RUNX1 target genes in an intermediate state

Class:IdCatalystActivityReference:9643364
_displayNamehistone methyltransferase activity (H3-K4 specific) of H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] Histone arginine methylation keeps RUNX1 target genes in an intermediate state
_timestamp2019-04-04 17:05:18
catalystActivity[CatalystActivity:8936487] histone H3K4 methyltransferase activity of H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
created[InstanceEdit:9643047] Wu, G, 2019-04-04
literatureReference[LiteratureReference:8936397] Histone arginine methylation keeps RUNX1 target genes in an intermediate state
(catalystActivityReference)[Reaction:8936481] Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by histone methyltransferase activity (H3-K4 specific) of H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] Histone arginine methylation keeps RUNX1 target genes in an intermediate state (9643364)