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Details on Person endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen] The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
| Class:Id | CatalystActivityReference:9643201 |
|---|---|
| _displayName | endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen] The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues |
| _timestamp | 2019-04-04 17:05:18 |
| catalystActivity | [CatalystActivity:983143] endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen] |
| created | [InstanceEdit:9643047] Wu, G, 2019-04-04 |
| literatureReference | [LiteratureReference:982961] The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues [LiteratureReference:982896] An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides [LiteratureReference:985505] ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum |
| (catalystActivityReference) | [BlackBoxEvent:983158] Trimming of peptides in ER [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by endopeptidase activity of ERAP1/2 [endoplasmic reticulum lumen] The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues (9643201)
