Reactome: A Curated Pathway Database
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Details on Person Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane

Class:IdRegulationReference:9641826
_displayNamePositive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
_timestamp2019-04-04 17:04:23
created[InstanceEdit:9641190] Wu, G, 2019-04-04
literatureReference[LiteratureReference:1449644] Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
[LiteratureReference:1449646] Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells
[LiteratureReference:1458569] Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation
[LiteratureReference:1458557] Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells
regulation[PositiveRegulation:1458572] Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]'
(regulationReference)[BlackBoxEvent:2316352] SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane [Homo sapiens]
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No pathways have been reviewed or authored by Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane (9641826)