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Details on Person Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
| Class:Id | RegulationReference:9641826 |
| _displayName | Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane |
| _timestamp | 2019-04-04 17:04:23 |
| created | [InstanceEdit:9641190] Wu, G, 2019-04-04 |
| literatureReference | [LiteratureReference:1449644] Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane [LiteratureReference:1449646] Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells [LiteratureReference:1458569] Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation [LiteratureReference:1458557] Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells |
| regulation | [PositiveRegulation:1458572] Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' |
| (regulationReference) | [BlackBoxEvent:2316352] SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane [Homo sapiens] |
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No pathways have been reviewed or authored by Positive regulation by 'GGC-RAB8A,10,13,14:GTP [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane (9641826)