Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Misfolded proteins from cellular stress are destined for deg...
| Class:Id | Summation:9641121 |
|---|---|
| _displayName | Misfolded proteins from cellular stress are destined for deg... |
| _timestamp | 2019-06-14 15:03:42 |
| created | [InstanceEdit:9641131] Varusai, Thawfeek, 2019-04-04 |
| modified | [InstanceEdit:9641152] Varusai, Thawfeek, 2019-04-04 [InstanceEdit:9649433] Varusai, Thawfeek, 2019-06-14 |
| text | Misfolded proteins from cellular stress are destined for degradation via ubiquitination. The E2 ubiquitin conjugating enzymes UBE2N/UBE2V1 and E3 ligase enzyme Parkin recruit and tag multiple K63-linked ubiquitin molecules to the misfolded proteins. Subsequently, the polyubiquitinated proteins dissociate from the E2/E3 system and are driven to degradation (Olzmann JA et al. 2007). |
| (summation) | [Reaction:9641109] PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Misfolded proteins from cellular stress are destined for deg... (9641121)
