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Details on Person Misfolded proteins in the cytosol are tagged with ubiquitin ...

Class:IdSummation:9641115
_displayNameMisfolded proteins in the cytosol are tagged with ubiquitin ...
_timestamp2019-04-04 09:59:00
created[InstanceEdit:9641131] Varusai, Thawfeek, 2019-04-04
modified[InstanceEdit:9641152] Varusai, Thawfeek, 2019-04-04
textMisfolded proteins in the cytosol are tagged with ubiquitin molecules via the E2 UBE2N/UBE2V1 conjugation complex and E3 ligase Parkin. Misfolded proteins bind Parkin and subsequently Parkin transfers ubiquitin from E2 complex to the proteins (Olzmann JA et al. 2007).
(summation)[Reaction:9641111] Parkin transfers Ub to misfolded proteins [Homo sapiens]
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