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Details on Person Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

Class:IdLiteratureReference:9641088
_displayNameParkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
_timestamp2019-04-04 08:31:35
author[Person:5336439] Olzmann, James A
[Person:5658546] Li, Lian
[Person:9641098] Chudaev, Maksim V
[Person:9641095] Chen, Jue
[Person:9641093] Perez, Francisco A
[Person:9641086] Palmiter, Richard D
[Person:5658536] Chin, Lih-Shen
created[InstanceEdit:9641087] Varusai, Thawfeek, 2019-04-04
journalJ. Cell Biol.
modified[InstanceEdit:9641107] Varusai, Thawfeek, 2019-04-04
pages1025-38
pubMedIdentifier17846173
titleParkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
volume178
year2007
(literatureReference)[Reaction:9641089] Parkin binds Ub:UBE2N:UBE2V1 [Homo sapiens]
[Reaction:9641096] Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub [Homo sapiens]
[Reaction:9641109] PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 [Homo sapiens]
[Reaction:9641111] Parkin transfers Ub to misfolded proteins [Homo sapiens]
[Polymerisation:9641127] Ub:misfolded proteins polymerize to PolyUb:misfolded proteins [Homo sapiens]
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