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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q10CI8 ORC5

Class:IdReferenceGeneProduct:9640637
_chainChangeLogchain:1-524 for 9640637 added on Thu May 2 2019
_displayNameUniProt:Q10CI8 ORC5
_timestamp2023-11-03 18:32:21
chainchain:1-524
checksum6CE37D71C4326B4C
commentFUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.SUBCELLULAR LOCATION Expressed at low levels in the shoot apical meristem (SAM), leaves, ears and roots.INDUCTION Reduced expression upon sucrose depletion-mediated cell proliferation arrest, and accumulates after sucrose treatment.SIMILARITY Belongs to the ORC5 family.SEQUENCE CAUTION Truncated N-terminus.
created[InstanceEdit:9640652] Gupta, Parul, 2019-04-03
descriptionrecommendedName: fullName evidence="6"Origin of replication complex subunit 1 shortName evidence="6"OsORC1
geneNameORC5
LOC_Os03g55200
Os03g0759500
OsJ_12664
OSJNBb0048A17.14
identifierQ10CI8
isSequenceChangedFALSE
keywordATP-binding
DNA replication
Nucleotide-binding
Nucleus
Reference proteome
modified[InstanceEdit:9645038] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9750299] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameORC5
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierORC5_ORYSJ
A0A0P0W393
B9F5T4
Q852R2
Q94HA9
sequenceLength524
species[Species:1250427] Oryza sativa subsp. japonica
(referenceEntity)[EntityWithAccessionedSequence:9640694] ORC5 [nucleoplasm] [Oryza sativa]
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No pathways have been reviewed or authored by UniProt:Q10CI8 ORC5 (9640637)