Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q8GSL4 ORC6

Class:IdReferenceGeneProduct:9640635
_chainChangeLogchain:1-295 for 9640635 added on Thu May 2 2019
_displayNameUniProt:Q8GSL4 ORC6
_timestamp2023-11-03 18:32:21
chainchain:1-295
checksum01712BCEC186E4EF
commentFUNCTION Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.SUBUNIT Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.SUBCELLULAR LOCATION Belongs to the ORC6 family.
created[InstanceEdit:9640652] Gupta, Parul, 2019-04-03
descriptionrecommendedName: fullName evidence="4"Origin of replication complex subunit 6 shortName evidence="4"OsORC6
geneNameORC6
LOC_Os07g43540
Os07g0628600
OsJ_25222
P0011H09.106
P0506F02.120
identifierQ8GSL4
isSequenceChangedFALSE
keywordDNA replication
DNA-binding
Nucleus
Reference proteome
modified[InstanceEdit:9645038] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9750299] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameORC6
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierORC6_ORYSJ
A0A0P0X8V6
sequenceLength295
species[Species:1250427] Oryza sativa subsp. japonica
(referenceEntity)[EntityWithAccessionedSequence:9640752] ORC6 [nucleoplasm] [Oryza sativa]
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No pathways have been reviewed or authored by UniProt:Q8GSL4 ORC6 (9640635)