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Details on Person Accumulation of excessive reactive oxygen species (ROS) with...

Class:IdSummation:9639720
_displayNameAccumulation of excessive reactive oxygen species (ROS) with...
_timestamp2019-06-14 15:03:30
created[InstanceEdit:9639702] Varusai, Thawfeek, 2019-03-19
modified[InstanceEdit:9639738] Varusai, Thawfeek, 2019-03-19
[InstanceEdit:9649433] Varusai, Thawfeek, 2019-06-14
textAccumulation of excessive reactive oxygen species (ROS) within cells results in oxidative stress. This stress can trigger proteins misfolding and make them dysfunctional. Cilia proteins are damaged when subjected to oxidative stress and may be targeted to the autophagy machinery. This results in the shortening of the cilium (Lam HC et al. 2013, Kim JI et al. 2013).
(summation)[Reaction:9639715] ROS positively regulates misfolding of cilia proteins [Mus musculus]
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