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Details on Person ROS positively regulates misfolding of cilia proteins

Class:Id	Reaction:9639698
_displayName	ROS positively regulates misfolding of cilia proteins
_doRelease	TRUE
_timestamp	2020-04-07 10:37:07
authored	[InstanceEdit:9639658] Varusai, Thawfeek, 2019-03-18
compartment	[Compartment:18730] cilium
created	[InstanceEdit:9639702] Varusai, Thawfeek, 2019-03-19
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
inferredFrom	[Reaction:9639715] ROS positively regulates misfolding of cilia proteins [Mus musculus]
input	[DefinedSet:9639672] Cilia proteins [cilium] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9639687] Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction [LiteratureReference:9639679] Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys
modified	[InstanceEdit:9639738] Varusai, Thawfeek, 2019-03-19 [InstanceEdit:9640103] Varusai, Thawfeek, 2019-03-21 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9655715] Varusai, Thawfeek, 2019-07-25 [InstanceEdit:9658415] D'Eustachio, Peter, 2019-08-13 [InstanceEdit:9663819] Varusai, Thawfeek, 2019-10-13 [InstanceEdit:9664481] Varusai, Thawfeek, 2019-10-23 [InstanceEdit:9664529] Varusai, Thawfeek, 2019-10-25 [InstanceEdit:9667360] Varusai, Thawfeek, 2019-11-12 [InstanceEdit:9682019] Varusai, Thawfeek, 2020-04-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ROS positively regulates misfolding of cilia proteins
output	[DefinedSet:9639713] Misfolded cilia proteins [cilium] [Homo sapiens]
regulatedBy	[PositiveRegulation:9639703] Positive regulation by 'ROS [cilium]'
regulationReference	[RegulationReference:9641393] Positive regulation by 'ROS [cilium]' Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
releaseDate	2019-12-10
reviewed	[InstanceEdit:9682018] Metzakopian, Emmanouil, 2019-05-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9639725] R-HSA-9639698.3
summation	[Summation:9639676] Accumulation of excessive reactive oxygen species (ROS) with...
(hasEvent)	[Pathway:9639650] Ciliophagy [Homo sapiens] [Pathway:9646399] Aggrephagy [Homo sapiens]
(precedingEvent)	[Reaction:9640114] Misfolded proteins translocate from cilium to cytosol [Homo sapiens]
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No pathways have been reviewed or authored by ROS positively regulates misfolding of cilia proteins (9639698)