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Details on Person Expression of EGFR regulated by NR3C2

Class:Id	BlackBoxEvent:9639547
_displayName	Expression of EGFR regulated by NR3C2
_doRelease	FALSE
_timestamp	2019-03-13 17:49:46
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9639546] Shamovsky, Veronica, 2019-03-13
input	[EntityWithAccessionedSequence:8874800] EGFR gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9638965] Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter [LiteratureReference:9638970] Mineralocorticoid receptor interaction with SP1 generates a new response element for pathophysiologically relevant gene expression
modified	[InstanceEdit:9641190] Wu, G, 2019-04-04
name	Expression of EGFR regulated by NR3C2
output	[EntityWithAccessionedSequence:179837] EGFR [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9638973] NR3C2, SP1 bind the EGFR gene [Homo sapiens] [Reaction:9035351] NR3C2 dimerizes [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9638971] Positive gene expression regulation by 'NR3C2:NR3C2 ligand:SP1:EGFR gene [nucleoplasm]'
regulationReference	[RegulationReference:9642710] Positive gene expression regulation by 'NR3C2:NR3C2 ligand:SP1:EGFR gene [nucleoplasm]' Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9639548] R-HSA-9639547.1
(hasEvent)	[Pathway:9635721] NR3C2 regulates gene expression linked to vascular remodeling [Homo sapiens]
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No pathways have been reviewed or authored by Expression of EGFR regulated by NR3C2 (9639547)