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Details on Person Under acidic or anaerobic conditions iron may be prevalent i...
| Class:Id | Summation:9638530 |
|---|---|
| _displayName | Under acidic or anaerobic conditions iron may be prevalent i... |
| _timestamp | 2025-01-29 10:07:39 |
| created | [InstanceEdit:9638466] Pardo, Agustin, 2019-03-05 |
| modified | [InstanceEdit:9911796] Stephan, Ralf, 2024-06-06 [InstanceEdit:9915279] Stephan, Ralf, 2024-07-04 [InstanceEdit:9937072] Stephan, Ralf, 2025-01-29 |
| text | Under acidic or anaerobic conditions iron may be prevalent in the reduced ferrous form (Fe2+). The virulence of pathogenic bacteria is enhanced by Fe2+ import (Stojiljkovic et al. 1993). Ferrous iron is thought to diffuse freely through the outer membrane porins. Transport through the plasma membrane is facilitated by the EfeUOB system which is dysfunctional in many non-pathogenic bacteria due to a deletion mutation. In contrast, the EfeUOB operon of the enterohaemorrhagic strain, O157:H7, lacks any frameshift and is functional (Grosse et al., 2006; Cao et al. 2007). EfeUOB belongs to the Iron/Lead Transporter (ILT) family that has homologs in bacteria and fungi. |
| (summation) | [Reaction:9638493] efeUOB transport Fe2+ from periplasmic space to the cytosol [Escherichia coli] [Reaction:9911598] EfeUOB transport Fe2+ from periplasmic space to the cytosol [Homo sapiens] |
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No pathways have been reviewed or authored by Under acidic or anaerobic conditions iron may be prevalent i... (9638530)
