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Details on Person UniProt:P0AEL6 fepB

Class:IdReferenceGeneProduct:9638375
_chainChangeLogsignal peptide:1-26 for 9638375 added on Thu May 2 2019;chain:27-318 for 9638375 added on Thu May 2 2019
_displayNameUniProt:P0AEL6 fepB
_timestamp2024-08-09 19:30:17
chainsignal peptide:1-26
chain:27-318
checksum807676D03A508079
commentFUNCTION Part of the ABC transporter complex FepBDGC involved in ferric enterobactin uptake (PubMed:3011753). Binds ferric enterobactin (PubMed:10986237, PubMed:25173704, PubMed:7551033). Can also bind ferric enantioenterobactin, the left-handed stereoisomer of the natural E.coli siderophore, and the apo-siderophore, enterobactin, but does not bind ferric agrobactin (PubMed:10986237).SUBUNIT The complex is composed of two ATP-binding proteins (FepC), two transmembrane proteins (FepD and FepG) and a solute-binding protein (FepB).SUBCELLULAR LOCATION Expression is regulated by iron, via the regulatory protein Fur (PubMed:2139473, PubMed:2529253). Induced by hydroxyurea (PubMed:20005847).SIMILARITY Belongs to the bacterial solute-binding protein 8 family.
created[InstanceEdit:9638341] Koile, Daniel, 2019-03-05
descriptionrecommendedName: fullName evidence="11"Ferric enterobactin-binding periplasmic protein FepB
geneNamefepB
b0592
JW0584
identifierP0AEL6
isSequenceChangedFALSE
keyword3D-structure
Ion transport
Iron
Iron transport
Periplasm
Reference proteome
Signal
Transport
modified[InstanceEdit:9645038] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9767224] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
namefepB
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierFEPB_ECOLI
P14609
Q2MBK9
sequenceLength318
species[Species:159879] Escherichia coli
(referenceEntity)[EntityWithAccessionedSequence:9638312] FepB [periplasmic space] [Escherichia coli]
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No pathways have been reviewed or authored by UniProt:P0AEL6 fepB (9638375)