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Details on Person B3GAT3 dimer transfers GlcA to tetrasaccharide linker

Class:IdReaction:9638064
_displayNameB3GAT3 dimer transfers GlcA to tetrasaccharide linker
_doReleaseFALSE
_timestamp2025-06-03 07:17:51
authored[InstanceEdit:1889961] Jassal, B, 2011-11-01
catalystActivity[CatalystActivity:9638063] galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity of B3GAT3:Mn2+ dimer [Golgi membrane]
compartment[Compartment:20699] Golgi membrane
[Compartment:17963] Golgi lumen
created[InstanceEdit:9638065] Jassal, Bijay, 2019-02-25
edited[InstanceEdit:1889961] Jassal, B, 2011-11-01
input[DefinedSet:2064214] Gal-Gal-Xyl-proteins [Golgi lumen] [Homo sapiens]
[SimpleEntity:1889970] UDP-GlcA [Golgi lumen]
isChimericFALSE
literatureReference[LiteratureReference:1889979] Structural basis for acceptor substrate recognition of a human glucuronyltransferase, GlcAT-P, an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1
[LiteratureReference:1889986] Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues
modified[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9953525] Stephan, Ralf, 2025-06-03
nameB3GAT3 dimer transfers GlcA to tetrasaccharide linker
A glucuronate moiety is the fourth addition to the tetrasaccharide linker
output[SimpleEntity:205687] UDP [Golgi lumen]
[DefinedSet:2064225] GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] [Homo sapiens]
precedingEvent
releaseDate2012-06-12
reviewed[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9638069] R-HSA-9638064.2
summation[Summation:9638066] Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransf...
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No pathways have been reviewed or authored by B3GAT3 dimer transfers GlcA to tetrasaccharide linker (9638064)