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Details on Person EsxA translocates from Mtb cytosol to the host's ER

Class:IdBlackBoxEvent:9637651
_displayNameEsxA translocates from Mtb cytosol to the host's ER
_doReleaseTRUE
_timestamp2024-07-06 08:10:04
authored[InstanceEdit:9637647] Stephan, Ralf, 2019-02-19
compartment[Compartment:70101] cytosol
[Compartment:17957] endoplasmic reticulum lumen
created[InstanceEdit:9637648] Pardo, Agustin, 2019-02-19
disease[Disease:1660556] tuberculosis
edited[InstanceEdit:9637648] Pardo, Agustin, 2019-02-19
input[EntityWithAccessionedSequence:9636668] EsxA [cytosol] [Mycobacterium tuberculosis]
isChimericFALSE
literatureReference[LiteratureReference:9637606] The ESAT-6 protein of Mycobacterium tuberculosis interacts with beta-2-microglobulin (β2M) affecting antigen presentation function of macrophage
modified[InstanceEdit:9637737] Jassal, Bijay, 2019-02-19
[InstanceEdit:9638882] Jassal, Bijay, 2019-03-06
[InstanceEdit:9640155] Pardo, Agustin, 2019-03-22
[InstanceEdit:9664479] Jassal, Bijay, 2019-10-23
[InstanceEdit:9665619] Jassal, Bijay, 2019-10-31
[InstanceEdit:9665684] Matthews, Lisa, 2019-10-31
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9915435] Stephan, Ralf, 2024-07-06
nameEsxA translocates from Mtb cytosol to the host's ER
output[EntityWithAccessionedSequence:9637622] EsxA [endoplasmic reticulum lumen] [Mycobacterium tuberculosis]
relatedSpecies[Species:176806] Mycobacterium tuberculosis
releaseDate2019-12-10
reviewed[InstanceEdit:9664478] Deffur, Armin, Wilkinson, RJ, 2019-10-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9637656] R-HSA-9637651.3
summation[Summation:9637624] Mtb secreted 6 kDa early secretory antigenic target (EsxA) s...
(hasEvent)[Pathway:9637628] Modulation by Mtb of host immune system [Homo sapiens]
(precedingEvent)[Reaction:9637635] EsxA binds B2M [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919432] Update Tracker - [BlackBoxEvent:9637651] EsxA translocates from Mtb cytosol to the host's ER - v90:[modifyText]
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