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Details on Person acyl-CoA (8-3)-desaturase activity

Class:IdGO_MolecularFunction:9637467
_displayNameacyl-CoA (8-3)-desaturase activity
_timestamp2025-05-21 23:03:43
accession0062076
created[InstanceEdit:9637466] Weiser, JD
definitionCatalysis of the reaction: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA) and add a fourth double bond (a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA).
ecNumber1.14.19.44
modified[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
nameacyl-CoA (8-3)-desaturase activity
referenceDatabase[ReferenceDatabase:1] GO
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No pathways have been reviewed or authored by acyl-CoA (8-3)-desaturase activity (9637467)