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Details on Person PPE2:KPNA1:KPNB1 translocates to the nucleus

Class:Id	BlackBoxEvent:9636247
_displayName	PPE2:KPNA1:KPNB1 translocates to the nucleus
_doRelease	TRUE
_timestamp	2019-10-31 17:28:04
authored	[InstanceEdit:9635702] Stephan, Ralf, 2019-02-06
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9636267] Koile, Daniel, 2019-02-12
disease	[Disease:1660556] tuberculosis
edited	[InstanceEdit:9636267] Koile, Daniel, 2019-02-12
input	[Complex:9636269] PPE2:KPNA1:KPNB1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9636246] The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production
modified	[InstanceEdit:9636283] Koile, Daniel, 2019-02-12 [InstanceEdit:9638882] Jassal, Bijay, 2019-03-06 [InstanceEdit:9640147] Pardo, Agustin, 2019-03-22 [InstanceEdit:9640155] Pardo, Agustin, 2019-03-22 [InstanceEdit:9664479] Jassal, Bijay, 2019-10-23 [InstanceEdit:9665619] Jassal, Bijay, 2019-10-31 [InstanceEdit:9665684] Matthews, Lisa, 2019-10-31 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PPE2:KPNA1:KPNB1 translocates to the nucleus
output	[Complex:9636243] PPE2:KPNA1:KPNB1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9636251] PPE2 binds KPNA1:KPNB1 [Homo sapiens]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2019-12-10
reviewed	[InstanceEdit:9664478] Deffur, Armin, Wilkinson, RJ, 2019-10-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9636273] R-HSA-9636247.2
summation	[Summation:9636244] PPE family protein PPE2 is translocated to the phagocyte's n...
(hasEvent)	[Pathway:9636249] Inhibition of nitric oxide production [Homo sapiens]
(precedingEvent)	[Reaction:9636242] PPE2:KPNA1:KPNB1 dissociates, releasing PPE2 into the nucleus [Homo sapiens]
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