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Details on Person ATF4 binds the CEBPB gene

Class:Id	Reaction:9635936
_displayName	ATF4 binds the CEBPB gene
_doRelease	TRUE
_timestamp	2019-11-20 13:49:15
authored	[InstanceEdit:9635874] May, Bruce, 2019-02-09
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9635911] May, Bruce, 2019-02-10
edited	[InstanceEdit:9635874] May, Bruce, 2019-02-09
input	[EntityWithAccessionedSequence:3858376] CEBPB gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381016] ATF4 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9635882] Amino-acid limitation induces transcription from the human C/EBPbeta gene via an enhancer activity located downstream of the protein coding sequence
modified	[InstanceEdit:9635963] May, Bruce, 2019-02-10 [InstanceEdit:9644934] May, Bruce, 2019-04-29 [InstanceEdit:9661248] May, Bruce, 2019-09-15 [InstanceEdit:9668176] May, Bruce, 2019-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ATF4 binds the CEBPB gene
output	[Complex:9635875] ATF4:CEBPB gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:381128] Translation of ATF4 [Homo sapiens] [Reaction:381111] EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK [Homo sapiens] [Reaction:9633008] p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 [Homo sapiens] [Reaction:9648888] p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) [Homo sapiens]
releaseDate	2019-12-10
reviewed	[InstanceEdit:9661246] Bruhat, Alain, 2019-09-15 [InstanceEdit:9668172] Staschke, Kirk A, 2019-11-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9635938] R-HSA-9635936.3
summation	[Summation:9635961] ATF4 binds an enhancer downstream of the protein coding regi...
(hasEvent)	[Pathway:9633012] Response of EIF2AK4 (GCN2) to amino acid deficiency [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9635918] Expression of CEBPB in response to stress [Homo sapiens]
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No pathways have been reviewed or authored by ATF4 binds the CEBPB gene (9635936)