Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ATF4 and a CEBP protein bind the TRIB3 promoter

Class:Id	Reaction:9635927
_displayName	ATF4 and a CEBP protein bind the TRIB3 promoter
_doRelease	TRUE
_timestamp	2019-11-20 13:48:03
authored	[InstanceEdit:9635874] May, Bruce, 2019-02-09
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9635911] May, Bruce, 2019-02-10
edited	[InstanceEdit:9635874] May, Bruce, 2019-02-09
inferredFrom	[Reaction:9644330] Atf4 and Cebpg bind the Trib3 gene [Mus musculus]
input	[EntityWithAccessionedSequence:5649928] TRIB3 gene [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:381016] ATF4 [nucleoplasm] [Homo sapiens] [DefinedSet:9654226] CEBPB,CEBPG,DDIT3 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9635933] Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions [LiteratureReference:9635894] TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
modified	[InstanceEdit:9635963] May, Bruce, 2019-02-10 [InstanceEdit:9644351] May, Bruce, 2019-04-12 [InstanceEdit:9654236] May, Bruce, 2019-07-17 [InstanceEdit:9661248] May, Bruce, 2019-09-15 [InstanceEdit:9664255] May, Bruce, 2019-10-22 [InstanceEdit:9668176] May, Bruce, 2019-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ATF4 and a CEBP protein bind the TRIB3 promoter
output	[Complex:9635876] ATF4:CEBPB,CEBPG,DDIT3:TRIB3 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:381128] Translation of ATF4 [Homo sapiens] [Reaction:381111] EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK [Homo sapiens] [Reaction:9633008] p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 [Homo sapiens] [Reaction:9648888] p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) [Homo sapiens]
releaseDate	2019-12-10
reviewed	[InstanceEdit:9661246] Bruhat, Alain, 2019-09-15 [InstanceEdit:9664254] Chen, Jane-Jane, 2019-10-22 [InstanceEdit:9668172] Staschke, Kirk A, 2019-11-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9635949] R-HSA-9635927.3
summation	[Summation:9635957] ATF4 binds composite CEBP-ATF elements located in three 33-b...
(hasEvent)	[Pathway:9633012] Response of EIF2AK4 (GCN2) to amino acid deficiency [Homo sapiens] [Pathway:9648895] Response of EIF2AK1 (HRI) to heme deficiency [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9635912] Expression of TRIB3 in response to stress [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by ATF4 and a CEBP protein bind the TRIB3 promoter (9635927)