Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person The complex of ESAT-6-like proteins EsxG:EsxH respond to ste...

Class:IdSummation:9635647
_displayNameThe complex of ESAT-6-like proteins EsxG:EsxH respond to ste...
_timestamp2024-07-06 08:13:37
created[InstanceEdit:9635645] Pardo, Agustin, 2019-02-06
modified[InstanceEdit:9636549] Koile, Daniel, 2019-02-13
[InstanceEdit:9915435] Stephan, Ralf, 2024-07-06
textThe complex of ESAT-6-like proteins EsxG:EsxH respond to sterile membrane damage, recognizing either the damaged membrane itself or recruited proteins (Mittal et al. 2016). The EsxG:EsxH complex disrupts membrane repair and host trafficking by binding to hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/Hrs) a component of human ESCRT (Mehra et al. 2013).
(summation)[Reaction:9635667] EsxG:EsxH binds HGS [Homo sapiens]
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